Virtue 340B
Mastering the 340B Maze

The 340B drug pricing program serves as a financial lifeline, enabling hospitals and clinics to stretch limited resources and reinvest the savings into patient care. But there is a trade-off: covered entities must remain compliant amid tight regulations while directing the maximum possible benefits to patients. Ambiguities in the statute create uncertainty and elevate operational risk— making expert guidance essential to safeguard compliance and fulfill the program’s mission.

Virtue 340B strikes that perfect balance by offering customized solutions to optimize the 340B program. As a premier consulting and audit partner, the company helps healthcare providers identify and address compliance gaps through objective, data-driven evaluations of their 340B operations. Its primary client base includes hospitals and health centers participating in the program, with a focus on rural hospitals, HRSA-funded community clinics, and others with federal grants.

“Our goal is to empower our clients to deliver cost-effective, comprehensive care for their patients. By going beyond risk mitigation, we explore opportunities to optimize 340B savings without compromising regulatory integrity,” says Edward Vargas, founder and CEO.

Building on that foundation, the company’s services fall into three main categories. Independent 340B compliance assessments offer one-time, objective audits to identify compliance gaps and areas of risk. To maintain consistent adherence, the quarterly review model in continuous monitoring services audits claims and evaluates program performance for timely adjustments. Customized consulting services further provide targeted support, addressing specific aspects of a client’s 340B program to optimize utilization while maintaining operational alignment.

From the initial conversation to the final audit report, Virtue 340B follows a structured process focused on proactive risk identification and performance improvement, demonstrating its commitment to transparency.

Behind such precision and efficiency is the company’s highly skilled team, which brings decades of industry experience in 340B program management, auditing, and consulting. The team has delivered real-world results by driving significant cost savings, streamlining workflows, and reducing risk—supporting covered entities across the U.S.

One such example is an independent 340B compliance audit conducted last year for a health center in western New York. The client faced unclear compliance status and had no recent audit oversight. The center lacked a structured approach to optimize its 340B program, especially regarding clinic-administered drugs. Virtue 340B delivered a comprehensive compliance audit, identified areas for improvement, and confirmed operational alignment. To support sustainable program enhancements, it also performed an opportunity analysis and developed a collaborative oversight plan.

The result was undeniable: the health center captured over 80 percent of 340B savings by focusing on just 10 high-impact drugs. Drug inventory costs were reduced by more than 50 percent, and program savings increased—all without the need to add extra staff.

Backed by a proven track record, a growing team of experts, and a strong foundation of serving diverse healthcare entities, Virtue 340B is striving to cast a wider net across the industry. One such initiative is a self-published book by the founder, 340B Mastery: Transforming Risk into Reward in Pharmacy Program Management, reinforcing the company’s credibility in auditing and maintaining compliant 340B operations. It also plans to expand into larger urban hospitals and health systems as part of its growth trajectory and near-term goals.

By setting the standard for transparency, integrity, and efficiency, Virtue 340B stays true to its mission: empowering health systems and 340B pharmacy leaders through compliance-focused consulting that ultimately maximizes patient impact.